Biophysics Applications

Dual Polarisation Interferometry (DPI) is an analytical technique used to understand the subtle, yet essential, relationship between biomolecular structure and function in real time. DPI, the core technology of the AnaLight® instrument range, has been successful across a range of Biophysical applications, including proteins, nucleic acids, lipids and carbohydrates.

As an interferometric technique, DPI has a wide dynamic range so can accommodate a broad range of typical solvents, such as DMSO and EtOH, and buffers and buffer additives. This means that the DPI user can carry out experiments in the conditions of choice rather than those dictated by the limitations of other techniques.

The unique, absolute measurements provided by DPI enable the researcher to question and understand the intimate links between the structural changes in biomolecules and their functions and interactions to an extent not previously available in a laboratory-based technique.

Select the application area of interest below to view a full listing of applications notes, these can be either downloaded or viewed online:

• Biomolecular Interaction Analysis
• Membrane Protein and Lipid Studies
• Drug Discovery and Development
  (Protein - Small Molecule Interactions)
• Protein - Metal Ion Interactions
• Biomolecular Structure and Stability
• Protein Crystallography Studies

For further information, or application discussions, please contact: applications@farfield-group.com