AnaLight® CrystaLight™
"Shed New Light on Crystallisation Processes"
The AnaLight® CrystaLight™ is designed to apply DPI's unique optical measurements to the detection and understanding of the earliest phases of protein crystallisation processes.
In simple terms, the AnaLight® CrystaLight™ is a 'molecular microscope' whose quantitative structural measurements can be compared directly with complementary techniques such as X-ray crystallography, circular dichroism and NMR spectroscopy, whilst also being capable of affinity and kinetic mass measurements at higher sensitivity than first-generation optical and acoustic biosensor technologies.
- Simultaneous surface imaging on two independent flow channels
- Contrast measurements provide key information on the onset of crystallisation
- Twin flow channels give parallel monitoring of crystallisation for control and comparison
- Independent sample loading and flow rate control to each flow cell
- Open fluidic design allows user-defined optimisation based on applications
- Software controlled sample injection and flow control for flexibility and precision at low volumes
- Accurate temperature control and rapid temperature stabilisation
- Search crystallisation space without the need for optically visible crystals on two parallel measurement channels
- Software gives option of automated reference channel subtraction when running parallel control experiments
- Contrast measurements distinguish easily between protein crystallisation and other macromolecular processes, such as aggregation and precipitation
- Provides a unique information set for the detection of crystallisation at the early nucleation stage, the onset of the crystallisation process
- Detects the onset of crystallisation up to 100x faster than polarised microscopy
- Provides the information to monitor crystallisation processes and the applications flexibility to develop and optimise crystallisation conditions in real time
View the full range of key biophysics applications for the AnaLight® instrument range
Full product specifications are found in the AnaLight® CrystaLight™ Product Information Sheet. Request a copy from sales@farfield-group.com
For more information on the suitability of the AnaLight® CrystaLight™ for your applications, please contact your local Farfield representative