AnaLight® BioFlex
"World's First Automated Biomolecular Structure-Function Assay Platform"
The AnaLight® BioFlex brings DPI's unique biomolecular structure-function measurements into discovery and development facilities with a need for automated sample throughput in a range of biophysical applications.
In simple terms, the AnaLight® BioFlex is a 'molecular microscope' whose quantitative structural measurements can be compared directly with complementary techniques such as such as X-ray crystallography, circular dichroism and NMR spectroscopy, whilst also being capable of affinity and kinetic mass measurements at higher sensitivity than first-generation optical or acoustic biosensor technologies.
- Automated sample loading for unattended throughput
- Autosampler provides precision sample loading from 50-vial, 96-well and 384-well sample formats
- Twin flow cells give simultaneous, parallel sample analysis for control and comparison
- Software provides integrated sample handling and data processing throughout
- Simultaneous measurement on three channels gives total confidence in data integrity
- Full intuitive method scripting for unattended operation with manual intervention feature during runs
- Wide dynamic range extends solvent and buffer handling capabilities
- Accurate temperature control and rapid temperature stabilisation
- Flexible range of analytical surfaces and reagents available to suit all applications
- Simple upgrade path from manual AnaLight® Bio200
- Instantaneous, quantitative measurement of biomolecular dimensions, fold density (RI) and mass on two parallel measurement surfaces with automated throughput
- Software gives option of automated reference channel subtraction when running parallel control experiments
- AnaLight® software provides comprehensive analysis of mass changes, affinity, interaction kinetics and structural behaviour in quantitative units
- Measures conformational changes in biomolecules as small as 0.1 Ångstrom as they happen, with or without any mass change
- Measures mass changes as low as 0.1 picogram/mm2 in real time, giving class-leading kinetic performance
- Provides a unique information set on the behaviour and interactions of biomolecules with industry-leading resolution
- Automated AnaChip™ and solvent calibration protocols ensure ultimate measurement accuracy
- Download or view AnaLight® BioFlex Product Information Sheet (72 Kb)
View the full range of key biophysics applications for the AnaLight® instrument range
For more information on the suitability of the AnaLight® BioFlex for your applications, please contact your local Farfield representative